For embryologists
When something in the lab goes wrong, start here.
Every lab troubleshoots by trial and error. This library turns that into a method: start from the problem, work through the likely factors, check each one against what the manufacturer actually says — and write it down so it never has to be rediscovered.
Manufacturer-neutral. No endorsements. Always follow the instructions for use (IFU) of your own products.
Problem-first guides
3 guidesFertilisation rate has dropped — where to look, in order
A structured way through a sudden fall in 2PN rate after ICSI or IVF: patient mix first, then timing, then the sperm side, then media, oil and dishes, then equipment and technique.
Work through itBlastocyst rate has fallen — separating patient factors from culture problems
When fertilisation is fine but embryos stall between day 3 and day 5: how to tell patient mix from a culture-system problem, and the incubator, media, oil, and handling factors to check.
Work through itPost-warming survival has fallen — vitrification, warming, storage or handling?
When blastocysts stop surviving warming as they should: how to split the problem into the freezing side, the storage side and the warming side, and what to check in each.
Work through it
Media, equipment & technique registry
Browse all →One page per product or technique: how it's used, its typical failure modes, what to check first, and where the IFU lives. Kept current by a weekly scan of manufacturer updates and society guidance.
Free tool
CAPA Builder — reconstruct the fix, then document it
You tell it what you changed and roughly when. It lines those changes up against when your numbers recovered, suggests the likely cause, and writes the corrective and preventive actions in an audit-ready form. Free, like everything here.
Get the CAPA Builder