EMBRYOLOGICS
Registry

Registry · equipment · Various (e.g. MVE, Taylor-Wharton, Cryotherm)

Cryostorage dewars / LN₂ tanks

Long-term storage of vitrified oocytes and embryos at −196°C in liquid or vapour phase.

Clinical review pending·1 min read·Updated 2026-08-16

What it is and how it's used

Safe as long as the LN₂ level stays above the minimum for the storage arrangement. Vacuum failure is slow and silent; boil-off rate is the early warning.

Typical failure modes

  • Level allowed to fall below the top of stored devices (vapour warming).
  • Vacuum loss: rising boil-off, frost on neck/shoulders.
  • Late refills over holidays; alarm not connected/tested.
  • Devices dislodged during moves.

What to check first

  1. Daily level log with a marked minimum line; refill schedule adherence.
  2. Consumption trend over months.
  3. Alarm test records; back-up tank and LN₂ supply plan.

IFU and practice notes

Follow the manufacturer's guidance for fill levels and inspection; keep an inventory that maps every device to a position.

Neutral, and the IFU wins

This page summarises common experience across labs and is not manufacturer guidance. Always follow the current instructions for use for the exact product and version you have, and validate any change of product or protocol before patient use. Corrections and additions are welcome — tell us.

This page is educational and general. It is not a substitute for advice from your own clinic or the manufacturer's instructions for use.